12/20/2023 0 Comments Arsenic poisoning antidotepyrexia) occurring after the initial injection of dimercaprol should be assessed before continuing treatment. in arsine poisoning and some cases of arsenic poisoning. Dimercaprol Injection may not be effective in cases of concomitant renal failure, e.g. It should be discontinued or continued with extreme caution if acute renal insufficiency develops during therapy. There are no specific data on the use of dimercaprol in the elderly but since it is eliminated via the kidney, it should be used with caution in this age group.ĭimercaprol Injection should be used with care in patients with hypertension or impaired renal function. However, in severe acute poisoning, single doses up to 5 mg per kg bodyweight may be required initially.ĭimercaprol Injection is well tolerated by children and the dosage should be calculated on the basis of bodyweight, using the same unit dose per kg of bodyweight as for an adult under similar clinical circumstances. As a general guide, single doses should not exceed 3 mg per kg bodyweight. Within the above dose range, individual dosage should be calculated on a bodyweight basis and will depend upon the severity of symptoms and the causative agent. 400 - 800 mg, in divided doses, on the first day.Ģ00 - 400 mg, in divided doses, on the second and third days.ġ00 - 200 mg, in divided doses, on the subsequent days.
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